Table 3. Summarised description of our patients and published ones.

	Our patients	Previous reportsa	Overall
Genderb	11M/4F	11M/8F	22M/12F
Parental originc	7P/2M	7P/1M	14P/3M
Perinatal data
Hypotonia	3/11	12/20	48%
Feeding difficulties	4/13	4/20	24%
Clinical features
Development delay	13/13	16/17	97%
Learning disabilities	14/14	15/16	97%
Behavioural problems	10/12	7/16	61%
Sleep disorders	4/12	1/19	16%
Hyperphagia	5/14	6/8	50%
Obesity	10/14	10/17	65%
Craniofacial features
Rounded face/full cheeks	11/12	6/19	55%
Skull features	7/15	11/19	53%
Philtrum features	6/15	6/19	35%
Bulbous nose	5/15	2/19	21%
Abnormal extremities	10/14	10/17	65%
Hands	6/14	7/17	42%
Feet	4/14	5/17	29%
Genital anomalies	2/15	2/20	11%
Abnormal brain MRI	1/7	8/10	53%
Vision anomalies	8/14	7/13	56%

Main features in our patients and previously reported ones, with molecularly defined 6q16.2 and/or 6q16.3 deletions.

^aPrevious reports.^{3, 13, 15, 16, 17, 18, 21, 22, 23, 24, 25}

^bM: Male, F: Female.

^cP: Paternal, M: Maternal.