Table 7. Summary of Various Reports of Disease-specific iPSC Generation.
This table is a summary of the various diseases that have had iPSCs generated from patient-specific cells. This table is not an exhaustive list and is meant to be representative.
Reference | Species | Disease |
---|---|---|
Liver Disease-specific Applications | ||
(Hansel et al., 2013) | Human | CN-1 |
(Rashid et al., 2010) | Human | A1AT, FH, GSD, CN-1, tyrosinemia |
(Ghodsizadeh et al., 2010) | Human | Tyrosinemia, GSD, progressive familial hereditary cholestasis, CN-1 |
(Yusa et al., 2011) | Human | A1AT |
(Zhang et al., 2011) | Human | Wilson’s disease |
Other Disease Applications | ||
(Park et al., 2008a) | Human | adenosine deaminase deficiency-related severe combined immunodeficiency, Shwachman-Bodian-Diamond syndrome, Gaucher disease type III, muscular dystrophy, Parkinson disease, Huntington disease, juvenile-onset type 1 diabetes mellitus, down syndrome/trisomy 21, carrier state of Lesch-Nyhan syndrome |
(Kazuki et al., 2010) | Mouse and Human | muscular dystrophy |
(Soldner et al., 2009) | Human | Parkinson’s disease (transgene-free) |
(Ebert et al., 2009) | Human | spinal muscular atrophy |
(Lee et al., 2009) | Human | familial dysautonomia |
(Meng et al., 2010) | Mouse | lysosomal storage disorders |
(Pasca et al., 2011) | Human | Timothy syndrome |
(Raya et al., 2009) | Human | Fanconi anemia |
(Sebastiano et al., 2011) | Human | sickle cell anemia |
(Dimos et al., 2008) | Human | Amyotrophic lateral sclerosis |
(Sanchez-Danes et al., 2012) | Human | Genetic and sporadic Parkinson’s disease |
(Lee et al., 2014) | Human | Rheumatoid arthritis and osteoarthritis |