Table 3.
Nominal (n=1559) |
AV adjusted (n=2294) |
p value (vs. nominal) |
VV adjusted (n=604) |
p value (vs. nominal) |
AV and VV adjusted (n=852) |
p value (vs. nominal) |
|
---|---|---|---|---|---|---|---|
Follow-up, days | 956 (328) | 983 (322) | 0.009 | 944 (344) | 0.5 | 952 (330) | 0.8 |
PCT activity | 7 (4.2) | 7.5 (4.6) | 0.0005 | 6.9 (4.3) | 0.8 | 7.3 (4.2) | 0.2 |
Change from baseline | 0.00 (1.4) | −0.03 (1.6) | 0.5 | −0.09 (1.5) | 0.2 | 0.03 (1.5) | 0.8 |
HRV SDANN | 73.6 (20.7) | 72.9 (18.8) | 0.5 | 73 (21.4) | 0.7 | 73.5 (22.4) | 0.9 |
Change from baseline | 0.83 (9.8) | 0.92 (10.2) | 0.9 | 0.21 (9.7) | 0.5 | 0.71 (10.2) | 0.9 |
HRV footprint | 29 (8.9) | 28.8 (9) | 0.8 | 29.1 (10.5) | 0.9 | 28.9 (9.6) | 0.9 |
Change from baseline | 0.24 (3.8) | 0.14 (3.9) | 0.7 | 0.63 (0.9) | 0.3 | −0.13 (4.5) | 0.2 |
HRV mean HR | 77 (8) | 77.1 (8.2) | 0.8 | 77.2 (10.2) | 0.8 | 76.5 (9.5) | 0.4 |
Change from baseline | −0.45 (3.4) | −0.47 (3.7) | 0.9 | −0.28 (4.4) | 0.6 | −0.08 (4.9) | 0.2 |
AF burden >5 % | 27.7 % | 17.9 % | <0.0001 | 28.3 % | 0.8 | 18.9 % | <0.0001 |
Change from baseline | 4.00 % (21.0 %) | 4.00 % (18.0 %) | 0.8 | 3.00 % (19.0 %) | 0.9 | 4.00 % (17.0 %) | 0.6 |
Atrial pacing (%) | 33 (37) | 31 (35) | 0.6 | 29 (36) | 0.001 | 32 (37) | 0.8 |
Change from baseline | 1.00 (32) | 4.00 (29) | 0.03 | 2.00 (32) | 0.9 | 5.00 (32) | 0.06 |
LV pacing <95 % | 17.3 % | 17.8 % | 0.6 | 19.2 % | 0.3 | 18.5 % | 0.4 |
Change from baseline | 0.00 % (13.0 %) | −1.00 % (14.0 %) | 0.8 | −1.00 % (12.0 %) | 0.046 | −2.00 % (15.0 %) | 0.09 |
ATP therapy | 27.6 % | 29.5 % | 0.2 | 31.0 % | 0.1 | 32.7 % | 0.006 |
Shock during follow-up | 13.1 % | 13.4 % | 0.8 | 12.9 % | 0.9 | 16.7 % | 0.01 |
Death | 18.6 % | 19.1 % | 0.7 | 20.7 % | 0.3 | 19.2 % | 0.7 |
Numbers are % or mean (standard deviation)
AV atrioventricular timing, VV ventricular-to-ventricular timing, ATP anti-tachycardia pacing, AF atrial fibrillation, LV left ventricular, HRV heart rate variability, SDANN standard deviation of the average NN intervals, HR heart rate