Table 1. Down-regulation of Androgen-Responsive Gene Expression by TQ and AT.
| Gene | Symbol3 | Fold decrease in [mRNA]1, 2 | |
|---|---|---|---|
| TQ | AT | ||
| Transmembrane 4 L Six Family Member 1 | TM4SF1 | 22.2 | 1.1 |
| Prostate Specific Antigen (PSA)4 | KLK3 | 9.1 | 1.1 |
| Kallikrein-Related Peptidase 2 | KLK2 | 7.1 | 1.0 |
| FK506 Binding Protein 5 | FKBP5 | 2.9 | 1.3 |
| Prostein | SLC45A3 | 2.6 | 1.2 |
| Acid Phosphatase, Prostate | ACPP | 2.4 | 1.2 |
| NK3 Homeobox 1 | NKX3-1 | 1.9 | 1.1 |
| Prostate-Specific Membrane Antigen | FOLH1 | 1.5 | 1.1 |
1 Analysis by quantitative PCR (see Materials and Methods).
2 Compared to control, vehicle-treated LNCaP cells.
3 National Center for Biotechnology Information Gene Official Symbol (Name/Gene ID).
4 NCBI Official Full Name is kallikrein-related peptidase 3.