Figure 2.

AUC improvements over baseline model from models predicting 5-year mortality as a function of self-reported indicators and biomarkers. In addition to age, the baseline model controls for sex, ethnicity (Mainlander vs Taiwanese), urban residence, education, social integration and perceived availability of social support. The self-reported health indicators include global self-assessed health, an index of mobility limitations, history of diabetes, history of cancer, number of hospitalizations in the past 12 months and smoking status. The biomarkers comprise eight standard cardiovascular/metabolic risk factors, four inflammatory markers, four neuroendocrine markers and three other markers that do not represent a common biological subsystem. The biomarker summary score counts the number of markers (out of 19) for which the respondent exhibits a high-risk level, which is defined by established cutoffs for the standard cardiovascular/metabolic factors and C-reactive protein (CRP) and by the high-risk quartile for the remaining markers. AUC, area under the receiver operating characteristic (ROC) curve. Source: Glei et al.¹⁵