Table 2.
Correlations of clinicopathological parameters and expression level of lncRNA CRNDE-h in patients with CRC (n=142)
| Variables | No of cases | IncRNA CRNDE-h expression | P-value |
|---|---|---|---|
| Age (years) | |||
| <60 | 80 | 1.466 (0.844–3.182) | 0.177 |
| ≥60 | 62 | 2.043 (0.996–4.424) | |
| Sex | |||
| Male | 87 | 1.686 (1.136–3.898) | 0.247 |
| Female | 55 | 1.427 (0.659–3.167) | |
| Tumor location | |||
| Rectum | 93 | 1.628 (0.858–3.733) | 0.613 |
| Colon | 49 | 1.651 (1.251–3.315) | |
| Tumor differentiation | |||
| Poor | 31 | 2.875 (1.016–5.229) | 0.218 |
| Moderate | 83 | 1.427 (0.855–3.133) | |
| Well | 28 | 1.694 (1.125–3.554) | |
| Lymphovascular invasion | |||
| No | 91 | 1.682 (1.121–3.674) | 0.413 |
| Yes | 51 | 1.398 (0.744–3.220) | |
| T stage | |||
| T1–T2 | 30 | 1.321 (0.574–2.414) | 0.067 |
| T3–T4 | 112 | 1.687 (1.053–3.899) | |
| Regional lymph node metastasis | |||
| Negative | 76 | 1.353 (0.885–2.277) | 0.006* |
| Positive | 66 | 2.385 (1.138–4.808) | |
| Distant metastasis | |||
| No | 112 | 1.408 (0.774–2.850) | 0.003* |
| Yes | 30 | 2.972 (1.603–5.315) | |
| Tumor size | |||
| <5 cm | 87 | 1.419 (0.724–2.468) | 0.017* |
| ≥5 cm | 55 | 2.384 (1.243–4.418) |
Notes:
*
P-values are statistically significant. Data presented as median (25%–75% interquartile range).
Abbreviations: lncRNA, long noncoding RNA; CRNDE-h, colorectal neoplasia differentially expressed – h; CRC, colorectal cancer.