Table 3.

Univariate and multivariate Cox proportional hazards regression model analysis of overall survival in patients with CRC (n=142)

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P-value	HR	95% CI	P-value
Age	1.042	0.659–1.648	0.860
Sex	0.927	0.578–1.486	0.753
Tumor location	0.820	0.502–1.340	0.429
Tumor differentiation	1.130	0.786–1.625	0.509
Lymphovascular invasion	0.807	0.499–1.305	0.383
T stage	2.086	1.071–4.062	0.031*	1.365	0.624–2.986	0.436
Regional lymph node metastasis	2.683	1.680–4.284	<0.001*	3.012	1.746–5.197	<0.001*
Distant metastasis	3.102	1.905–5.053	<0.001*	2.599	1.496–4.516	0.001*
Tumor size	1.529	0.970–2.411	0.067
High CRNDE-h expression	2.906	1.794–4.709	<0.001*	2.173	1.282–3.684	0.004*

Note:

^*P-values are statistically significant.

Abbreviations: CI, Confidence interval; HR, hazard ratio; lncRNA, long noncoding RNA; CRNDE-h, colorectal neoplasia differentially expressed – h; CRC, colorectal cancer.