Table 3. HSC frequency following in vivo deletion of Meis1 in primary recipients.
CD45.2+ | HSC Frequency | Upper 95% CI | Lower 95% CI | |
---|---|---|---|---|
MxCre/Meis1+/- | BULK | 1 / 1.4 x105 | 1 / 3.1 x104 | 1 / 6.2 x105 |
MxCre/Meis1-/- | p<0.06 | 1 / 1.8 x107 | 1 / 2.5 x106 | 1 / 1.3 x108 |
MxCre/Meis1+/- | SORTED | 1 / 1.6 x105 | 1 / 4.0 x104 | 1 / 6.5 x105 |
MxCre/Meis1-/- | p<1x10-125 | 1 / 1.0 x106 | 1 / 2.8 x105 | 1 / 3.6 x106 |