Table 2. Alcohol consumptions and thyroid cancer stratified by histologic types (papillary and follicular thyroid cancer); T-CALOS April 2010–April 2014.

	Men				Women
	PTC1		FTC1		PTC1		FTC1
	Case	OR (95% CI)2,3	Case	OR (95% CI) 2,3	Case	OR (95% CI) 2,3	Case	OR (95% CI) 2,3
Alcohol intake (g) per event
Never	76	1.00 (Reference)	2	1.00 (Reference)	1,079	1.00 (Reference)	32	1.00 (Reference)
0–50	83	0.72 (0.52–1.02)	7	1.54 (0.28–8.50)	413	0.86 (0.76–0.98)	16	1.16 (0.60–2.27)
51–150	197	1.23 (0.91–1.67)	8	1.83 (0.32–10.28)	118	1.34 (1.09–1.66)	4	1.44 (0.44–4.74)6
151+4	19	2.17 (1.23–3.83)	1	5.36 (0.34–85.68)	7	3.56 (1.50–8.46)	0
p-trend5		0.004		0.578		0.232
Duration (years)
Never	76	1.00 (Reference)	2	1.00 (Reference)	1,079	1.00 (Reference)	32	1.00 (Reference)
0–20	115	0.82 (0.58–1.16)	2	0.26 (0.03–2.43)	351	0.76 (0.66–0.87)	15	1.07 (0.52–2.20)
21–30	100	0.81 (0.58–1.15)	6	1.70 (0.24–11.92)	190	1.42 (1.20–1.69)	5	1.50 (0.60–3.78)6
31+4	125	1.75 (1.23–2.48)	13	13.27 (1.11–158.28)	72	2.38 (1.81–3.12)	2
p-trend5		0.006		0.018		<0.001		0.458

Abbreviations: PTC = papillary thyroid cancer; FTC = follicular thyroid cancer; OR = odds ratio; 95% CI = 95% confidence interval.

¹. Subjects with missing information for alcohol intake per event with FTC (5 men and 4 women) and PTC (50 men and 136 women) were identified.

². Conditional logistic regression models adjusted for education level, marital status, smoking, regular exercise, and history of hypertension and dyslipidemia.

³. No significant p-heterogeneity detected in the comparison of the ORs for PTC and FTC.

⁴. Due to insufficient power in analyses of the FTC patients and their matched controls, the highest cutoff values were changed to a drinking duration of 21+ years and 51 g of alcohol intake per event.

⁵. A p-trend was calculated for dose response associations.

⁶. ORs were calculated after merging the two cells of (51+ for alcohol intake amounts (g) per event and 21+ for the duration (years) of drinking) due to the limited number of cases.