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. 2016 Mar 17;11(3):e0151896. doi: 10.1371/journal.pone.0151896

Table 2. Clinical characteristics of the audited cases (n = 621).

Average* Inter-hospital range P-Value
Age (years) 68.3 (9.8) 64.7–69.7 NS
Male gender (n) 527 (84.9) 51.7–94.8 < 0.001
Current smokers (n) 142 (22.9) 13.8–37.5 < 0.001
Tobacco history (pack-year) 54.7 (30.5) 42.5–66.6 < 0.001
Comorbidities (Charlson) 2.15 (1.5) 1.8–2.4 NS
Psychiatric comorbidities (n) 126 (20.3) 12.3–24.1 NS
Cardiovascular comorbidities (n) 163 (26.2) 18.2–37.5 NS
Previous neoplasms (n) 92 (14.8) 8.6–21.0 NS
Time from diagnosis (years) 5.5 (5.9) 1.06–6.9 0.033
Previous hospitalizations (n) 0.9 (1.6) 0.1–1.3 < 0.001
Body mass index (kg/m2) 28.2 (5.3) 26.0–29.6 0.009
FVC (%) 74.6 (20.7) 63.7–98.4 < 0.001
FEV1 (%) 51.9 (19.7) 42.7–59.1 0.001

* Average value expressed as the mean (standard deviation) or absolute (relative) frequency depending on the nature of the variable.

Calculated for the variability between centers using ANOVA or Chi-square, depending on the nature of the variable.