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. 2016 Mar 17;11(3):e0151896. doi: 10.1371/journal.pone.0151896

Table 5. Recommendations regarding treatment monitoring.

Recommendation Average value* Inter-hospital range P value
Q8. GOLD 2013. At each visit, determine current smoking status and smoke exposure:
 • Smoking status verified 591 (95.2) 72.4–100 < 0.001
 • Pack-years calculated 558 (89.9) 68.8–100 < 0.001
 • Both items evaluated 533 (85.8) 62.1–100 < 0.001
Q9. GOLD 2013 recommends monitoring of:
 • Dosages of various medications: ICS dose recorded (n = 397) 372 (93.7) 50–100 < 0.001
 • Adherence to the regimen 327 (52.7) 3.4–92.6 < 0.001
 • Inhaler technique Not recorded
 • Effectiveness of the current regime at controlling symptoms: dyspnea recorded 560 (90.2) 69.1–100 < 0.001
 • Side effects of treatment 145 (23.3) 4.9–66.7 < 0.001
 • All four items recorded 93 (15.0) 0–44.4 < 0.001

* Average value expressed as the mean (standard deviation) or absolute (relative) frequency depending on the nature of the variable.

Calculated for the variability between centers using ANOVA or Chi-square, depending on the nature of the variable. Percentages refer to the whole population (n = 621) unless otherwise indicated. GOLD 2013: Global Initiative for Obstructive Lung Disease 2013 [19]; SEPAR 2009: SEPAR Health-Care Quality Standards 2009 [21]; GesEPOC 2012: Spanish National Guideline for COPD [22].