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. 2016 Mar 17;11(3):e0151621. doi: 10.1371/journal.pone.0151621

Fig 4. Sdc’s cytoplasmic domain influences Sdc’s subcellular localization.

Fig 4

(A) In wildtype larvae, Sdc colocalizes with HRP at the 3rd instar larval NMJ on muscles 6/7. (B) Muscle expression of a Sdc ΔCyto construct has diminished synaptic localization whereas expression of a construct lacking either C1 (C) or C2 (D) show intracellular accumulation of protein (arrows) in addition to the synaptic localization. Both the TM Swap construct (E) and the ΔEcto construct (F) exhibit similar subcellular localization to Sdc-FL.