Table 3. Specificity of javamide-II to Sirt1, 2 and 3 enzymes.

Inhibition ratio average is expressed as tested Sirt/Sirt2. Data are presented as mean ± SD (n = 6).

(μM)	Inhibition (%)
	Sirt1	Sirt2	Sirt3
0	0	0	0
0.1	5.2±3.4%	13±4.9%	1.5±1.7%
5.0	18±4.2%	39±5.9%	5.7±2.7%
10	24±5.8%	59±7.0%	8.0±3.7%
20	35±5.9%	69±8.7%	11±4.7%
40	59±6.1%	87±9.1%	28±6.1%
60	75±9.2%	98±9.7%	50±8.1%
Ratio Average	0.54	1	0.22