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Effect of Ang-(1-7) on ICa,L of cardiomyocytes: normal versus HF.
| ICa,L density (pA/pF) |
% Changes of ICa,L |
||
|---|---|---|---|
| Baseline | Ang-(1-7) | % | |
| Normal (N = 8; n = 18) | 8.0 ± 0.3 | 8.2 ± 0.2 | 2.5 |
| HF (N = 11; n = 32) | 5.0 ± 0.1$ | 6.4 ± 0.1* | 28.2$ |
Values are mean ± SEM.
p < 0.01, Ang-(1-7) versus baseline.
p < 0.01, HF versus normal.
HF, heart failure; ICa,L, L-type calcium current; N, number of animals; n, number of cells.
