Table 2.
Somatic mutation discovery statistics.
| C5 | D4 | B2 | B3 | B4 | E1 | Mean | ||
|---|---|---|---|---|---|---|---|---|
| SNVs | Mutation Calls | 112 | 50 | 50 | 68 | 70 | 61 | 68.5 |
| %FDR (n = 69) | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | -- | |
| %FNR | 21.4 | 20.8 | 19.0 | 18.9 | 19.2 | 22.8 | -- | |
| Estimated Mutations | 142 | 63 | 62 | 84 | 87 | 79 | 86.2 | |
|
| ||||||||
| Indels | Mutation Calls | 25 | 19 | 16 | 9 | 17 | 18 | 17.3 |
| %FDR (n = 23) | 4.3 | 4.3 | 4.3 | 4.3 | 4.3 | 4.3 | -- | |
| %FNR | 28.7 | 25.2 | 24.2 | 24.0 | 24.7 | 28.5 | -- | |
| Estimated Mutations | 34 | 24 | 20 | 12 | 21 | 24 | 22.5 | |
|
| ||||||||
| SVs | Validated Breakpoints | 3 | 0 | 7 | 1 | 0 | 3 | 2.3 |
| Validated Events | 2 | 0 | 3 | 1 | 0 | 3 | 1.5 | |
| %FNR | 13.5 | 12.4 | 13.1 | 8.6 | 8.4 | 13.4 | -- | |
| Estimated Breakpoints | 3 | 0 | 8 | 1 | 0 | 3 | 2.5 | |
|
| ||||||||
| MEIs | Validated Mutations | 1 | 1 | 0 | 2 | 0 | 0 | 0.7 |
| %FNR | 48.2 | 45.8 | 47.6 | 48.3 | 47.7 | 47.0 | -- | |
| Estimated Mutations | 2 | 2 | 0 | 4 | 0 | 0 | 1.3 | |
|
| ||||||||
| Total Estimated Mutations | 181 | 89 | 90 | 101 | 108 | 106 | 112.5 | |