Table 2.

Associations of TBS and prevalent radiographic vertebral fracture with incident major osteoporotic fractures, and model discrimination compared to base model^*†

Predictor	Model 1 (n=5862)	Model 2 (n=5829)	Model 3 (n=5829)
TBS (per sd decrease)	1.31 (1.20 to 1.43)		1.27 (1.17 to 1.39)
Prevalent Radiographic Vertebral Fracture		2.10 (1.63 to 2.70)	1.92 (1.49 to 2.48)
Harrell’s C (95% C.I.)	0.69^ (0.67 to 0.72)	0.69** (0.67 to 0.72)	0.70‡ (0.68 to 0.72)

^*Base model has log of FRAX with BMD 10 year major osteoporotic fracture risk as sole covariate; Harrell’s C for base model 0.69 (95% C,I, 0.66 to 0.71) .

^†Model 1 covariates: log of FRAX with BMD plus TBS; Model 2 covariates; log of FRAX with BMD plus prevalent radiographic vertebral fracture; Model 3 covariates; log of FRAX with BMD plus TBS and prevalent radiographic vertebral fracture

^{^}p-value=0.067 compared to base model

^**p-value=0.054 compared to base model

^‡p-value=0.010 compared to base model