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Categories of COA commonly used in malignant glioma clinical trials. The COA measures commonly used in glioma clinical trials can be divided into (A) PRO measures, (B) PerfO measures, and (C) ClinRO measures. PRO measures can include items assessing symptoms, functional limitations, and/or HRQoL. *Newly developed or in development. NCF, neurocognitive function; TMT, Trail Making Test; COWA, Controlled Oral Word Association.
