Table 1.
Resting | Exercising | Paired-Samples Difference* | P† | |
---|---|---|---|---|
ST, n = 9 | ||||
[Pi], mM | 3.37 ± 0.18 | 10.23 ± 1.10 | 6.9 ± 1.1 | <0.001 |
T1′, s | 4.5 ± 0.1 | 4.8 ± 0.3 | 0.3 ± 0.3 | 0.376 |
k′, min−1 | 2.98 ± 0.35 | 2.44 ± 0.16 | −0.54 ± 0.39 | 0.204 |
VPi-ATP, mM/min | 9.8 ± 0.9 | 25.0 ± 2.9 | 15.1 ± 3.5 | 0.003 |
PCr resynthesis, n = 11 | ||||
[PCr], mM | 32.9 ± 1.0 | 23.5 ± 1.2 | −9.3 ± 1.2 | <0.001 |
VATP, mM/min | ‡ | 16.5 ± 1.8 | ND |
ST, saturation transfer; Pi, inorganic phosphate; T1′, apparent longitudinal relaxation time of Pi in the presence of saturation of the γ-ATP resonance; k′, first-order rate constant; VPi-ATP, rate of Pi→ATP flux; [PCr], concentration of phosphocreatine; VATP, suprabasal oxidative rate of ATP synthesis determined from immediate end of exercise PCr resynthesis; ND, not determined.
Values are means ± SE. Data from volunteers in group B were averaged to provide one value per person to avoid inappropriate weighting.
Paired-samples difference (exercising-resting).
Paired-samples t-test to test for significant differences between rest and exercising conditions.
For comparison with exercising, this is 0.0 because VATP reflects suprabasal oxidative ATP synthesis. The net rate of basal oxidative ATP turnover is thought to be approximately 0.5 mM/min (16).