Table 2.

Effect of miR-155 deletion on lean and fat tissue in the AOM-DSS model of colon cancer

	Group
	WT	WT-A/D	miR-155−/− A/D
Spleen, mg	81 ± 2	194 ± 20*	212 ± 20*
Liver, mg	1,391 ± 70	1,507 ± 55	1,516 ± 36
Soleus, mg	8 ± 0.6	7±.4	7 ± 0.5
Gastrocnemius, mg	138 ± 2	122 ± 5*	113 ± 2*
Fat, mg
Epididymal	1,040 ± 129	557 ± 102*	400 ± 40*
Kidney	384 ± 44	160 ± 21*	144 ± 16*
Mesenchymal	633 ± 51	343 ± 39*	266 ± 36*

Values are means ± SE; n = 8–12 mice/group.

miR-155, microRNA-155; WT, wild-type; A/D, axoxymethane (AOM)-dextran sulfate sodium (DSS).

^*P < 0.05 vs. WT.