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. 2016 Jan 11;39:335–345. doi: 10.1007/s40264-015-0387-4

Table 3.

Top 10 product classes in African reports vs. RoW reports

ATC code Africa (%)a RoW (%)b
J05AF—nucleoside and nucleotide reverse transcriptase inhibitors 14,530 (14.04) 44,055 (0.38)
J05AG—non-nucleoside reverse transcriptase inhibitors 9407 (9.09) 26,107 (0.22)
J05AR—antivirals for the treatment of HIV infections, combinations 5692 (5.50) 34,927 (0.30)
J01EE—combinations of sulfonamides and trimethoprim, incl. derivatives 3082 (2.98) 81,206 (0.69)
C09AA—ACE inhibitors, plain 2503 (2.42) 154,176 (1.32)
S01AA—antibiotics 2340 (2.26) 179,635 (1.53)
J07AH—meningococcal vaccines 2308 (2.23) 48,480 (0.41)
L03AB—interferons 2130 (2.06) 211,098 (1.80)
J04AM—combinations of drugs for treatment of tuberculosis 1933 (1.87) 7043 (0.06)
D06AX—other antibiotics for topical use 1855 (1.79) 103,228 (0.88)

RoW rest of the world, ATC anatomic therapeutic chemical, ACE angiotensin-converting enzyme, ICSRs individual case safety reports

aPercentage includes all African ICSRs (n = 103,499) in VigiBase® (excluding Swaziland, n = 27)

bPercentage of all RoW ICSRs (n = 11,721,305) in VigiBase®