Table 4.
Top 10 product classes in RoW reports vs. African reports
| ATC code | RoW (%)a | Africa (%)b |
|---|---|---|
| L04AB—tumour necrosis factor alpha inhibitors | 619,737 (5.29) | 939 (0.91) |
| M02AA—antiinflammatory preparations, non-steroids for topical use | 265,138 (2.26) | 1350 (1.30) |
| L04AA—selective immunosuppressants | 243,382 (2.08) | 238 (0.23) |
| N06AB—selective serotonin reuptake inhibitors | 238,611 (2.04) | 718 (0.69) |
| C10AA—HMG CoA reductase inhibitors | 217,302 (1.85) | 936 (0.9) |
| M01AE—propionic acid derivatives | 214,595 (1.83) | 738 (0.71) |
| L03AB—interferons | 211,098 (1.80) | 2130 (2.06) |
| N05AH—diazepines, oxazepines, thiazepines and oxepines | 205,773 (1.76) | 650 (0.63) |
| N06AX—other antidepressants | 201,461 (1.72) | 1398 (1.35) |
| N03AX—other antiepileptics | 187,813 (1.60) | 959 (0.93) |
RoW rest of the world, ATC anatomic therapeutic chemical, ICSRs individual case safety reports
aPercentage of all RoW ICSRs (n = 11,721,305) in VigiBase®
bPercentage of all African ICSRs (n = 103,499) in VigiBase® (excluding Swaziland, n = 27)