Table 1.
Cardiac function and morphometry
Control | Tie2-Cre, Fgfr1f/f, Fgfr2f/f DCKO | |
---|---|---|
HR, beats/min | 631 ± 11 | 600 ± 12 |
LVPWd | 0.83 ± 0.03 | 0.77 ± 0.02 |
LVPWs | 1.43 ± 0.03 | 1.37 ± 0.06 |
IVSd | 0.84 ± 0.03 | 0.79 ± 0.02 |
IVSs | 1.48 ± 0.04 | 1.44 ± 0.05 |
LVIDd | 3.38 ± 0.08 | 3.29 ± 0.13 |
LVIDs | 1.50 ± 0.07 | 1.48 ± 0.1 |
LV mass | 93.7 ± 3.8 | 82.1 ± 5.5 |
RWT | 0.50 ± 0.02 | 0.48 ± 0.03 |
FS, % | 55.6 ± 1.6 | 55.0 ± 2.3 |
Data are mean ± SE; n = 8.
HR, heart rate; LVPWd, left ventricular posterior wall thickness in diastole; LVPWs, left ventricular posterior wall thickness in systole; IVSd, interventricular septum thickness in diastole; IVSs, interventricular septum thickness in systole; LVIDd, left ventricular internal diameter in diastole; LVIDs, left ventricular internal diameter in systole; LV mass, left ventricular; RWT, relative wall thickness; FS, fractional shortening.