Table 1.

Popliteal artery hemodynamics in nonheated and heated legs before, during, and after sitting for 3 h

		Basal Diameter, cm		Basal Blood Flow, ml/min		Hyperemic Blood Flow AUC, arbitrary units		Hyperemic Shear Rate AUC, arbitrary units		ANCOVA-Corrected FMD, %
		Nonheated	Heated	Nonheated	Heated	Nonheated	Heated	Nonheated	Heated	Nonheated	Heated
Supine	Pre-sit	0.59 ± 0.03	0.59 ± 0.03	58.9 ± 11.2	47.1 ± 5.0	45,990 ± 8,986	42,552 ± 6,725	34,259 ± 6,155	30,640 ± 4,018	6.9 ± 1.5	7.2 ± 1.5
Sitting	0 h	0.58 ± 0.02	0.57 ± 0.02	36.2 ± 5.5*†	79.4 ± 13.7
	1 h	0.59 ± 0.02	0.57 ± 0.02	32.3 ± 6.7*†	79.5 ± 16.3
	2 h	0.57 ± 0.02	0.57 ± 0.02	23.8 ± 3.7*†	72.8 ± 15.5
	3 h	0.57 ± 0.02	0.56 ± 0.02	25.1 ± 3.3*†	64.7 ± 12.4
Supine	Post-sit	0.58 ± 0.02	0.59 ± 0.03	30.7 ± 4.7*†	56.2 ± 11.8	20,715 ± 5,171*	28,749 ± 8,253	18,281 ± 3,846*	16,807 ± 4,531*	2.9 ± 1.5†	11.0 ± 1.5
	ANOVA	Time, P = 0.598		Time, P = 0.474		Time, P = 0.002		Time, P < 0.001		Time, P = 0.944
		Leg, P = 0.648		Leg, P = 0.003		Leg, P = 0.664		Leg, P = 0.485		Leg, P = 0.006
		Interaction, P = 0.526		Interaction, P < 0.001		Interaction, P = 0.399		Interaction, P = 0.798		Interaction, P = 0.011

Values are means ± SE. ANCOVA-corrected flow-mediated dilation (FMD) data are adjusted for hyperemic shear rate area under the curve (AUC).

^*P < 0.05, vs. pre-sit;

^†P < 0.05, between legs.