Table 1.
Basal Diameter, cm |
Basal Blood Flow, ml/min |
Hyperemic Blood Flow AUC, arbitrary units |
Hyperemic Shear Rate AUC, arbitrary units |
ANCOVA-Corrected FMD, % |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Nonheated | Heated | Nonheated | Heated | Nonheated | Heated | Nonheated | Heated | Nonheated | Heated | ||
Supine | Pre-sit | 0.59 ± 0.03 | 0.59 ± 0.03 | 58.9 ± 11.2 | 47.1 ± 5.0 | 45,990 ± 8,986 | 42,552 ± 6,725 | 34,259 ± 6,155 | 30,640 ± 4,018 | 6.9 ± 1.5 | 7.2 ± 1.5 |
Sitting | 0 h | 0.58 ± 0.02 | 0.57 ± 0.02 | 36.2 ± 5.5*† | 79.4 ± 13.7 | ||||||
1 h | 0.59 ± 0.02 | 0.57 ± 0.02 | 32.3 ± 6.7*† | 79.5 ± 16.3 | |||||||
2 h | 0.57 ± 0.02 | 0.57 ± 0.02 | 23.8 ± 3.7*† | 72.8 ± 15.5 | |||||||
3 h | 0.57 ± 0.02 | 0.56 ± 0.02 | 25.1 ± 3.3*† | 64.7 ± 12.4 | |||||||
Supine | Post-sit | 0.58 ± 0.02 | 0.59 ± 0.03 | 30.7 ± 4.7*† | 56.2 ± 11.8 | 20,715 ± 5,171* | 28,749 ± 8,253 | 18,281 ± 3,846* | 16,807 ± 4,531* | 2.9 ± 1.5† | 11.0 ± 1.5 |
ANOVA | Time, P = 0.598 | Time, P = 0.474 | Time, P = 0.002 | Time, P < 0.001 | Time, P = 0.944 | ||||||
Leg, P = 0.648 | Leg, P = 0.003 | Leg, P = 0.664 | Leg, P = 0.485 | Leg, P = 0.006 | |||||||
Interaction, P = 0.526 | Interaction, P < 0.001 | Interaction, P = 0.399 | Interaction, P = 0.798 | Interaction, P = 0.011 |
Values are means ± SE. ANCOVA-corrected flow-mediated dilation (FMD) data are adjusted for hyperemic shear rate area under the curve (AUC).
P < 0.05, vs. pre-sit;
P < 0.05, between legs.