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. 2015 Nov 18;310(2):R209–R216. doi: 10.1152/ajpregu.00305.2014

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Fig. 1. — Adm expression is drastically upregulated in the heart in an estrogen-dependent manner. A: quantitative RT-PCR (qRT-PCR) analysis for Adm from intact Adm^+/+ and Adm^hi/hi females normalized to calibrator. Additionally, Adm expression was analyzed by qRT-PCR in the hearts of ovariectomized (OVX) Adm^+/+ and Adm^hi/hi female mouse hearts and normalized to calibrator. B: qRT-PCR analysis of Adm levels from intact or OVX Adm^+/+ and Adm^hi/hi females in brain and spleen. C: qRT-PCR analysis of Adm levels from intact wild-type SvEV heart and uterus samples isolated during diestrus and estrus. All values represent means ± SE. *P < 0.05, **P < 0.01, ***P < 0.0001.