Table 1.

Twenty-four hour water and sodium balance listed for naïve Sprague-Dawley rats and Sprague-Dawley rats receiving a subcutaneous isotonic saline, 50:50 solution of DMSO and isotonic saline, NE, or NE and HCTZ infusion maintained on either a normal (0.6% NaCl) or high-salt (8% NaCl) diet for 14 days

	24-h H2O Balance, ml		24-h Sodium Balance, meq
Treatment	0.6% NaCl	8% NaCl	0.6% NaCl	8% NaCl
Naïve	19.1 ± 3.2	24.3 ± 4.0	0.6 ± 0.3	0.7 ± 0.2
Saline	26.2 ± 2.6	33.2 ± 4.2	0.5 ± 0.2	0.8 ± 0.2
DMSO Saline	21.5 ± 4.2	34.1 ± 6.0	1.0 ± 0.3	0.9 ± 0.2
NE, 600 ng/min	13.7 ± 2.6	19.5 ± 2.5	0.5 ± 0.2	0.5 ± 0.3
NE, 600 ng/min, and HCTZ, 4 mg·kg−1·day−1	16.3 ± 4.3	13.8 ± 2.3	0.2 ± 0.6	032 ± 0.6

Data are expressed as means ± SE (n = 6/group). NE, norepinephrine; HCTZ, hydrochlorothiazide.