Table 1. Haematological assessment after the administration of EGFR(2R)-lytic hybrid peptide to mice.
EGFR(2R)-lytic | Lytic | PBS | P | |
---|---|---|---|---|
WBC (×103/μL) | 2.5 ± 0.7 | 2.5 ± 0.2 | 3.1 ± 1.0 | 0.341 |
RBC (×104/μL) | 1002.2 ± 62.1 | 909.4 ± 138.4 | 907.8 ± 216.3 | 0.550 |
Hb (g/dL) | 16.1 ± 0.1 | 15.8 ± 0.7 | 15.3 ± 2.1 | 0.593 |
Hct (%) | 52.9 ± 3.3 | 49.1 ± 7.4 | 47.6 ± 10.5 | 0.549 |
Plt (×104/μL) | 81.5 ± 4.6 | 77.0 ± 11.6 | 69.8 ± 26.0 | 0.546 |
EGFR(2R)-lytic hybrid peptide (4 mg/kg) was intravenously injected into BALB/c mice twice a week for a total of six doses. Blood samples were obtained one day after the final intravenous injection of EGFR(2R)-lytic hybrid peptide. P-values were assessed by analysis of variance (ANOVA). Data are presented as the mean ± S.D. (n = 5). Note that EGFR(2R)-lytic hybrid peptide administration did not cause any haematological abnormalities in mice.