Fig. 4.
Phenylephrine (PE)-induced vasoconstriction curves in aortic rings with the PVAT removed (−PVAT) or intact (+PVAT) and in the presence or absence of the nonselective NOS inhibitor l-NAME in SS.13BN rats (n = 8–10) (A, B) and Dahl SS rats (n = 5–9) (C, D). AUC examining the effect of NOS inhibition on the vasoconstriction in aortic rings +PVAT (E) and −PVAT (F) without (−) or with (+) corresponding treatments. Number of multiple comparisons = 2. *P < 0.05 vs. SS.13BN aortic ring controls; †P < 0.05 vs. Dahl SS aortic ring controls.