Table 1.

Maximum vasoconstriction response (E_max) to phenylephrine in aortic preparations from SS.13^BN and Dahl SS rats with or without the perivascular adipose tissue or the endothelium in the presence or absence of NOS inhibition with l-NAME

Aortic Preparation	SS.13BN	Dahl SS
Emax; % Increase in Force Response to Phenylephrine
−PVAT+ENDO	109.2 ± 6.6	154.2 ± 9.0*
+PVAT+ENDO	70.6 ± 8.5†	69.0 ± 5.0†
+PVAT-ENDO	103.3 ± 10.0§	151.8 ± 10.1*§
−PVAT-ENDO	116.1 ± 7.4	148.9 ± 17.3
+PVAT+ENDO+l-NAME	97.9 ± 10.8§	174.8 ± 14.9*§
−PVAT+ENDO+l-NAME	121.2 ± 12.3	139.6 ± 10.4

Values are expressed as means ± SE. PVAT, perivascular adipose tissue; ENDO, endothelium; NOS, nitric oxide synthase; l-NAME, N^ω-Nitro-[SCAP]L[R]-arginine methyl ester.

^*P < 0.05 vs. respective SS.13^BN aortic preparation;

^†P < 0.05 vs. −PVAT+ENDO within same rat strain;

^§P < 0.05 vs. +PVAT+ENDO within same rat strain.

For SS.13BN rats, n = 8–10. For Dahl SS rats, n = 5–9.