Table 3.

Vascular sensitivity reported as logEC₅₀ to phenylephrine in aortic preparations from SS.13^BN rats and Dahl SS rats with or without PVAT or ENDO in the presence or absence of NOS inhibition with l-NAME

Aortic Preparation	SS-13BN	Dahl SS
LogEC50 (M) Determined From the % Increase in Force to Phenylephrine
−PVAT+ENDO	−7.06 ± 0.08	−7.55 ± 0.19*
+PVAT+ENDO	−5.97 ± 0.30†	−6.09 ± 0.14†
+PVAT-ENDO	−7.62 ± 0.21§	−8.21 ± 0.17*§
−PVAT-ENDO	−8.01 ± 0.16†	−8.31 ± 0.14*†
+PVAT+ENDO+l-NAME	−7.13 ± 0.19§	−7.79±.025§
−PVAT+ENDO+l-NAME	−7.83 ± 0.13†	−7.79 ± 0.09

Values are expressed as means ± SE.

^*P < 0.05 vs. respective SS.13^BN aortic preparation;

^†P < 0.05 vs. −PVAT+ENDO within same rat strain;

^§P < 0.05 vs. +PVAT+ENDO within same rat strain.

For SS.13BN rats, n = 8–10. For Dahl SS rats, n = 5–9.