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. 2016 Mar 18;6:23278. doi: 10.1038/srep23278

Figure 5. Hypothetical scenario of the HUVEC-mediated Treg cell induction.

Figure 5

During pregnancy, potential harmful maternal T cells are able to trespass the placenta. On the fetal side, the immigrated maternal T cells get in contact with HUVECs which are capable to induce their conversion into pregnancy-protective Treg cells. Female HUVECs possess a stronger potential to induce Treg cell conversion than male HUVECs.