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A mouse model expressing LOX in megakaryocytes and platelets. Immunoblot analysis of LOX expression in megakaryocytes (A) and platelets (B) of Pf4-Loxtg/tg mice and matching WT mice, generated as described under “Methods.” Megakaryocytes were purified by an albumin gradient, which enriches for large megakaryocytes ≥8N megakaryocytes. β-actin or glyceraldehyde-3-phosphate dehydrogenase (GAPDH) were used as loading controls.
