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Disruption of the GYS1 gene. LTR, long terminal repeat; β-Geo, β-galactosidase-neomycin phosphotransferase fusion gene (45); pA, polyadenylation sequence; SA, splice acceptor sequence; SD, splice donor sequence; PGK, phosphoglycerate kinase 1 promoter; BTK, Bruton's tyrosine kinase; OST, Omnibank sequence tag.
