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Rescue of perinatal lethality
| Mating | Genotype | No. of mice
|
|
|---|---|---|---|
| Actuala | Expectedb | ||
| MGSKO × MGSKO+/−/L25 | MGSKO−/− | 6 | 70 |
| MGSKO−/−/L25 | 19 | 70 | |
| MGSKO × MGSKO+/−/L30 | MGSKO−/− | 6 | 29 |
| MGSKO−/−/L30 | 28 | 29 | |
Number of mice which survived to genotyping age (2 weeks of age).
Number of pups predicted in the absence of lethality associated with the gene disruption.
