TABLE 4.
Transcripts increased more than twofold by sgf11 deletiona
| ORFb | Gene | Fold change | Molecular function |
|---|---|---|---|
| YJR057W | CDC8 | 6.8 | Thymidylate kinase |
| YGL231Cb | 6.6 | Unknown | |
| YOR254C | SEC63 | 6.2 | Protein transporter |
| YJR135W-A | TIM8 | 3.7 | Protein transporter |
| YJR108Wbc | ABM1 | 3.1 | Microtubule cytoskeleton organization and biogenesis |
| YHR077C | NMD2 | 3.0 | Protein binding |
| YLR449W | FPR4 | 2.7 | Peptidyl-prolyl cis-trans isomerase |
| YDL092W | SRP14 | 2.5 | Signal sequence binding |
| YEL045Cac | 2.4 | Unknown | |
| YJL104Wa | MIA1 | 2.3 | Protein transport |
| YIL016W | SNL1 | 2.2 | Interacts with the nuclear pore complex |
| YMR101C | SRT1 | 2.2 | Prenyltransferase |
| YNL212W | VID27 | 2.2 | Vacuole import and degradation |
| YGR128Ca | UTP8 | 2.1 | snoRNA binding |
| YNR057C | BIO4 | 2.1 | Dethiobiotin synthase |
| YIL069Ca | RPS24B | 2.0 | Structural constituent of ribosome |
| YMR251W-Aa | HOR7 | 2.0 | Responsiveness to hyperosmolarity |
The microarray results for the sgf11 deletion were compared to those previously reported for deletion of the SAGA components SPT20, GCN5, and SPT3 (27).
Superscript letters indicate transcript types as follows: a, transcripts regulated in the opposite direction by spt20 deletion; b, transcripts regulated in the opposite direction by gcn5 deletion; c, transcripts regulated in the opposite direction by spt3 deletion.