FIG. 3.

Locomotor activity in wild-type (solid squares) and mKat-2^−/−(open squares) mice at various ages. Values represent the number of sector border crossings during the 5-min testing session. The same wild-type (n = 17) and mKat-2^−/− (n = 18) mice were used longitudinally. One mKat-2^−/− mouse died at 5 months, and one mKat-2^−/− mouse and two wild-type mice died at 10 months. Data are expressed as the mean ± the standard error of the mean. *, P < 0.05 versus wild type (two-way ANOVA).