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. 2015 Nov 3;44(5):e42. doi: 10.1093/nar/gkv1144

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — EMERGE enhancer prediction is able to recognize and use tissue-specific signatures. Screenshot of the Pim1 locus, containing a validated heart and a validated brain enhancer located in close proximity. Using tissue-specific training data, the logistic regression approach of EMERGE is able to discriminate between heart and brain enhancers on the basis of their genomic signatures. The images of the enhancer screened transgenic embryos are taken from the Vista enhancer browser (reference in main text).