Table 1. Experimental and simulated translocation data for thymine-modified dsDNA.

Sample	<td> (μs)	v (nm/μs)	D (nm2/μs)	(ΔI / Io)E	(ΔI / Io)S
t-DNA	293 ± 5	0.189 ± 0.003	0.45 ± 0.04	0.516 ± 0.022	0.477 ± 0.008
h-DNA	159 ± 2	0.325 ± 0.004	0.71 ± 0.07	0.490 ± 0.024	0.454 ± 0.007
p-DNA	309 ± 4	0.169 ± 0.002	0.53 ± 0.05	0.498 ± 0.023	0.471 ± 0.007

Left: Experimental mean dwell time <t_d>, drift velocity v, diffusion coefficient D and fractional current blockade ΔI/I_o determined by best fits of dwell time (1D drift-diffusion) and current blockade (Gaussian) histograms. Right: MD simulation results for ΔI/I_o. For determination of uncertainties and details on the MD simulations, see Materials and Methods.