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. 2016 Jan 24;44(5):2439–2450. doi: 10.1093/nar/gkw018

Table 2. Minimal inhibitory concentration (MIC) values for selected PrAMPs against E. coli strains.

Peptide SQ110 (LPTD) (μM) SQ110 (μM)
Bac71–35 0.75 1.5
Onc112 0.75 12.5
Pyrrhocoricin 4 >25
Metalnikowin 62.5 >25
OncΔ15–19 25 >25
OncΔVD 62.5 >25
Onc10wt 1 25

The SQ110 LPTD strain is defective in the lipopolysaccharide assembly of the outer membrane and is more sensitive to some antibiotics (53).