Table 3. Ribosomal RNA mutations confer resistance to Onc112.

SQ110 DTCa	MIC [μmol L-1]
	Bac71–35	Onc112
“wild-type"b	0.75	3
2503C	0.75	12.5
2059C	0.75	12.5
2059C	0.75	12.5
2503C/2059G	0.75	50

^aThe E. coli strain SQ110 DTC and its derivatives used in these experiments carry a single chromosomal rrn allele and lack the tolC transporter gene (53).

^bThe parental SQ110 DTC strain lacking rRNA mutations is designated “wild type".