Figure 8. The CIA mouse model increases IL-1β and FGF-2 expression, as well as EPC homing in arthritic joints.

Paraffin sections of knee joint from control (Con) and CIA mice were stained with Safranin-O/Fast Green. Scale bar, 100 μm (A; n=4). Articular cartilage was IHC-stained with anti-IL-1β, anti-FGF-2, anti-CD34, anti-CD133, anti-VEGFR2 and anti-CD31 antibodies. Scale bar, 50 μm (B; n≥5).