TABLE 1.
Vector | FTI treatment (nM) | Relative colony counta | % Primitive CFU-Mb |
---|---|---|---|
MSCV-Neo | 0 | 1 | 1.7 ± 3.0 |
25 | 1.01 ± 0.09 | 1.6 ± 2.4 | |
50 | 0.98 ± 0.08 | 1.5 ± 4.1 | |
100 | 0.91 ± 0.09 | 1.0 ± 2.1 | |
200 | 0.9 ± 0.11 | 1.8 ± 4.5 | |
400 | 0.9 ± 0.08 | 1.9 ± 3.5 | |
MSCV-H-Ras-Neo | 0 | 1 | 2.8 ± 2.9 |
25 | 1.64 ± 0.21 | 10.2 ± 6.1 | |
50 | 2.01 ± 0.29 | 15.0 ± 7.7 | |
100 | 2.49 ± 0.48 | 15.1 ± 8.7 | |
200 | 1.93 ± 0.51 | 16.9 ± 7.4 | |
400 | 1.03 ± 0.32 | 9.3 ± 6.2 |
Number of colonies formed relative to the number formed without treatment. Values are means±SD.
Percentage of primitive monocytic colonies (high level of colony cellularity and high number of phenotypically primitive cells). Values are means ± SD.