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Impaired regulation of uterine PR expression by E2 in RIZ1 mutant mice. Uteri were collected and immunohistochemically analyzed for PR expression. (A) Estrogen-treated uteri (top panel, low magnification; bottom panel, high magnification). Randomly selected areas were photographed, and more than 1,000 cells from each compartment of the uteri of four mice in each group were counted. (B) Data are presented as the means ± the SEM. Inserted scale bars apply to both genotypes.
