Table 5.
Results of multiple linear regression analyzing the correlation between plantar pressure changes and clinical characteristic changes (n = 65)
| Plantar pressure parameters | Independent variables | β | P | R | R2 |
|---|---|---|---|---|---|
| Meta 1 | |||||
| Maximum force | Change of ABI | 0.137 | 0.048 | 0.876 | 0.767 |
| Change of BMI | 0.147 | 0.040 | |||
| Change of HbA1c | 0.364 | 0.001 | |||
| Change of NSS | 0.343 | 0.000 | |||
| Change of SCV | 0.244 | 0.018 | |||
| Maximum pressure | Change of BMI | 0.162 | 0.055 | 0.814 | 0.663 |
| Change of HbA1c | 0.366 | 0.002 | |||
| Change of NSS | 0.252 | 0.004 | |||
| Change of SCV | 0.285 | 0.016 | |||
| Meta 2 | |||||
| Maximum force | Calluses | 0.224 | 0.010 | 0.775 | 0.601 |
| Change of BMI | 0.281 | 0.004 | |||
| Change of NSS | 0.160 | 0.090 | |||
| Change of SCV | 0.416 | 0.000 | |||
| Infections | 0.251 | 0.004 | |||
| Maximum pressure | Change of BMI | 0.329 | 0.000 | 0.803 | 0.645 |
| Change of SCV | 0.559 | 0.000 | |||
| Infections | 0.255 | 0.002 | |||
| Pressure-time integral | Blisters | 0.244 | 0.014 | 0.695 | 0.483 |
| Change of cholesterol | 0.236 | 0.020 | |||
| Change of NSS | 0.269 | 0.011 | |||
| Change of SCV | 0.323 | 0.003 | |||
| Infections | 0.210 | 0.035 | |||
| Meta 3 | |||||
| Impulse | Calluses | 0.314 | 0.001 | 0.755 | 0.570 |
| Change of BMI | 0.319 | 0.001 | |||
| Change of NSS | 0.251 | 0.010 | |||
| Change of SCV | 0.303 | 0.002 | |||
| Maximum force | Calluses | 0.251 | 0.008 | 0.716 | 0.512 |
| Change of BMI | 0.400 | 0.000 | |||
| Change of NSS | 0.372 | 0.000 | |||
| Maximum pressure | Calluses | 0.165 | 0.064 | 0.756 | 0.572 |
| Change of BMI | 0.323 | 0.001 | |||
| Change of NSS | 0.257 | 0.009 | |||
| Change of SCV | 0.333 | 0.001 | |||
| Infections | 0.176 | 0.047 | |||
| Pressure-time integral | Calluses | 0.254 | 0.012 | 0.668 | 0.447 |
| Change of BMI | 0.271 | 0.014 | |||
| Change of NSS | 0.279 | 0.012 | |||
| Change of SCV | 0.238 | 0.029 | |||
| Meta 4 | |||||
| Maximum force | Calluses | 0.177 | 0.076 | 0.656 | 0.431 |
| Change of BMI | 0.404 | 0.000 | |||
| Change of NSS | 0.332 | 0.002 | |||
| Maximum pressure | Change of BMI | 0.403 | 0.000 | 0.677 | 0.458 |
| Change of NSS | 0.184 | 0.085 | |||
| Change of SCV | 0.302 | 0.005 | |||
| Pressure-time integral | Calluses | 0.224 | 0.040 | 0.578 | 0.334 |
| Change of BMI | 0.359 | 0.002 | |||
| Change of NSS | 0.242 | 0.034 | |||
| Medial heel Impulse | |||||
| Change of BMI | 0.400 | 0.000 | 0.706 | 0.499 | |
| Change of SCV | 0.418 | 0.000 | |||
| Infections | 0.169 | 0.071 | |||
| Lateral heel Impulse | |||||
| Change of BMI | 0.295 | 0.006 | 0.726 | 0.526 | |
| Change of cholesterol | 0.179 | 0.072 | |||
| Change of NSS | 0.178 | 0.087 | |||
| Change of SCV | 0.321 | 0.002 | |||
| Infections | 0.199 | 0.035 | |||
| Pressure-time integral | Change of BMI | 0.297 | 0.011 | 0.550 | 0.302 |
| Change of NSS | 0.370 | 0.002 |
The P values were derived from the significant associations between clinical characteristic changes and plantar pressure changes. P<0.1 was considered significant. Meta 1–Meta 4: Each of the first to the forth metatarsal heads; Medial heel: The medial portion of the heel; Lateral heel: The lateral portion of the heel; ABI: Ankle-brachial index; BMI: Body mass index; HbA1c: Hemoglobin A1c; NSS: Neuropathy symptom score; SCV: Sensory nerve conduction velocity of the left common peroneal nerve.