Table 2.
Population | Samples (n) | Risk allele frequency | P | OR (95% CI) | ||
---|---|---|---|---|---|---|
ALS | Controls | ALS | Controls | |||
Japanese (by Iida et al.) | ||||||
Discovery | 454 | 958 | 0.49 | 0.42 | 6.3×10−4 | 1.32 (1.13–1.55) |
Set 1 | 249 | 1030 | 0.51 | 0.43 | 1.80×10−3 | 1.37 (1.12–1.66) |
Set 2 | 602 | 2256 | 0.48 | 0.42 | 5.60×10−5 | 1.30 (1.14–1.48) |
Combined | 1305 | 4244 | 9.30×10−10 | 1.32 (1.21–1.44) | ||
Chinese (by Yang et al.) | ||||||
Replication | 301 | 457 | 0.52 | 0.46 | 0.035 | 1.25 (1.02–1.53) |
Chinese (in our study) | ||||||
Replication | 953 | 1039 | 0.50 | 0.51 | 0.54 | 0.94 (0.76–1.15) |
ALS: Amyotrophic lateral sclerosis; OR: Odds ratio; CI: Confidence interval.