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. 2015 Dec 20;128(24):3305–3309. doi: 10.4103/0366-6999.171421

Table 2.

Association of rs2275294 with ALS in Chinese compared to Japanese

Population Samples (n) Risk allele frequency P OR (95% CI)


ALS Controls ALS Controls
Japanese (by Iida et al.)
 Discovery 454 958 0.49 0.42 6.3×10−4 1.32 (1.13–1.55)
 Set 1 249 1030 0.51 0.43 1.80×10−3 1.37 (1.12–1.66)
 Set 2 602 2256 0.48 0.42 5.60×10−5 1.30 (1.14–1.48)
 Combined 1305 4244 9.30×10−10 1.32 (1.21–1.44)
Chinese (by Yang et al.)
 Replication 301 457 0.52 0.46 0.035 1.25 (1.02–1.53)
Chinese (in our study)
 Replication 953 1039 0.50 0.51 0.54 0.94 (0.76–1.15)

ALS: Amyotrophic lateral sclerosis; OR: Odds ratio; CI: Confidence interval.