Table 3.
Univariate and multivariate logistic regression analysis of LN metastasis
| Items | Univariate analysis | Multivariate analysis | Multivariate analysis† | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| Gender | ||||||
| Male | 1 | |||||
| Female | 0.504 (0.184–1.382) | 0.183 | ||||
| Age (years) | ||||||
| ≤60 | 1 | |||||
| >60 | 0.607 (0.181–2.032) | 0.418 | ||||
| Tumor location | ||||||
| Head | 1 | |||||
| Body/tail | 0.907 (0.148–1.240) | 0.899 | ||||
| CA125 | ||||||
| Normal | 1 | |||||
| Elevated | 2.750 (0.693–10.909) | 0.150 | ||||
| CA199 | ||||||
| Normal | 1 | 1 | 1 | |||
| Elevated | 4.714 (1.324–16.788) | 0.017 | 3.731 (0.869–16.021) | 0.077 | 2.832 (0.717–11.189) | 0.137 |
| Radiological size | ||||||
| ≤2.5 cm | 1 | 1 | 1 | |||
| >2.5 cm | 5.667 (1.527–21.032) | 0.010 | 2.456 (0.561–10.755) | 0.233 | 5.430 (1.431–20.603) | 0.013 |
| Symptoms | ||||||
| No | 1 | 1 | 1 | |||
| Yes | 3.345 (1.165–10.793) | 0.026 | 2.319 (0.670–8.032) | 0.184 | 3.366 (1.063–10.656) | 0.039 |
| Grading* | ||||||
| Grade 1 | 1 | 1 | / | / | ||
| Grade 2 | 6.125 (1.626–23.073) | 0.007 | 6.287 (1.615–24.478) | 0.008 | / | / |
| Grade 3 | 14.000 (3.324–58.969) | 0.000332 | 12.407 (2.827–54.450) | 0.001 | / | / |
*WHO 2010 classification;[22] †Multivariate analysis excluding tumor grade. OR: Odds ratio; 95% CI: 95% confidence interval; LN: Lymph node; WHO: World Health Organization.