Table 3.
Relationship of diagnosis levels and other variables
| Variables | Advanced-phase ALS (definite and probable) | Early-phase ALS (laboratory support and possible) | Statistical value | P |
|---|---|---|---|---|
| Course (years) | 1.00, 1.21, 2.88 | 1.00,2.00,4.80 | −0.871† | 0.384 |
| FRSr (U) | 34.88 (9.27) | 39.28 (7.59) | −2.75‡ | 0.007* |
| ER (mmol·L−1·min−1) | −17.33, −5.67, 4.00 | −25.17, −11.33, −3.50 | −1.971† | 0.049* |
| FVC (predicted %) | 88.50 (14.57) | 88.00 (13.90) | 0.502‡ | 0.619 |
| FRSr slope (U/year) | 4.53, 9.25, 17.99 | 2.06, 6.17, 15.75 | −1.397† | 0.163 |
| Average lactate (mmol/L) | 0.75 (0.25) | 0.78 (0.29) | −0.788‡ | 0.432 |
*P<0.05, statistical significance, two-tailed test. †Z test; ‡t-test. ER: Elimination rate; ALS: Amyotrophic lateral sclerosis; FVC: Forced vital capacity; FRSr: Functional rating scale-revised. Course, ER and FRSr slope are expressed as minimum, median and maximum values. FRSr, FVC (predicted %) and average lactate as mean (standard deviation).