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KlenTaq polymerase induces the dNaM-d5SICS UBP to adopt a natural, Watson-Crick-like structure. Structure of the polymerase-template binary complex (a), polymerase-template-d5SICSTP ternary complex (b), a superposition of binary and ternary complexes (c), and a superposition of the ternary complex where d5SICSTP is paired with dNaM and the ternary complex where dGTP is paired with dC (d). Reproduced from Betz, et al.[156]
