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. 2016 Jan 29;110(1):51–61. doi: 10.1093/cvr/cvw024

Figure 6.

Figure 6

CD206+ N2 neutrophils were activated in the post-MI LV, but not in circulation. (A) Circulating neutrophils at different time points post-MI were CD206−. n = 6–8 per group. (B) IL-10 (50 ng/mL) up-regulated the expression of the anti-inflammatory marker Il10; TGF-β1 (10 ng/mL) inhibited the expression of proinflammatory markers (Ccl3, Il1β, and Il12a) in neutrophils. The data were expressed as fold change (normalized to the unstimulated group). n = 4 mice per sample and n = 4 samples per group. *P < 0.05 vs. unstimulated. One-way ANOVA was used.