Table 1.
Haemodynamic parameters
| Heart samples | n | BW (g) | Pre-ischaemic equilibration |
End of reperfusion |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FR (mL/min) | HR (bpm) | LVDP (cmH2O) | +dp/dt | −dp/dt | FR (mL/min) | HR (bpm) | LVDP (cmH2O) | +dp/dt | −dp/dt | |||
| (cmH2O/ms) | (cmH2O/ms) | |||||||||||
| I/R-Control | 8 | 27.7 ± 0.6 | 2.7 ± 0.1 | 398 ± 11 | 123 ± 5 | 7.8 ± 0.2 | −5.6 ± 0.2 | 2.1 ± 0.1 | 360 ± 14 | 50 ± 3 | 4.3 ± 0.2 | −3.2 ± 0.1 |
| PostC-NaHS | 8 | 27.5 ± 0.6 | 2.5 ± 0.1 | 395 ± 13 | 121 ± 4 | 7.6 ± 0.5 | −5.4 ± 0.4 | 1.9 ± 0.1 | 356 ± 16 | 71 ± 5* | 5.7 ± 0.4* | −4.3 ± 0.3* |
| PostC-SNAP | 8 | 26.7 ± 0.5 | 2.5 ± 0.1 | 410 ± 10 | 121 ± 5 | 7.8 ± 0.5 | −5.2 ± 0.2 | 1.9 ± 0.1 | 350 ± 10 | 73 ± 6* | 5.7 ± 0.2* | −4.1 ± 0.2* |
| PostC-NaHS + SNAP | 8 | 27.2 ± 0.5 | 2.6 ± 0.1 | 381 ± 13 | 129 ± 4 | 8.1 ± 0.3 | −5.7 ± 0.2 | 2.0 ± 0.1 | 360 ± 10 | 96 ± 6** | 7.2 ± 0.3** | −5.4 ± 0.3** |
Values are mean ± SE.
n, number of hearts; BW, body weight; FR, flow rate; HR, heart rate (bpm); LVDP, left ventricular developed pressure; ±dp/dt, rates of pressure rise and fall, respectively.
*P < 0.01, vs. I/R-Control.
**P < 0.01 vs. PostC-NaHS or PostC-SNAP.