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. 2016 Mar 16;6(8):2624–2651. doi: 10.1002/ece3.2077

Figure 2.

Figure 2

Translated amino acid alignment of MHC‐DRB1 alleles from Gunnison's prairie dog, Cynomys gunnisoni (MhcCygu‐DRB1, alleles 01–06: GenBank accessions KU695893‐KU695896 and KR338362‐KR338363) and black‐tailed prairie dog, C. ludovicianus (MhcCylu‐DRB1, alleles 01–05: KR338364‐KR338368). Dots represent identity to the Cygu‐DRB*01 amino acid sequence at the top. Dashes indicate missing data. Shaded positions show putative antigen‐binding sites (ABS) after (Yuhki et al. 2008). None of the amino acid sites are predicted to be under positive selection in either prairie dog species. Other ground squirrels are included in the alignment, including spotted suslik (Spermophilus suslicus) Spsu‐DRB: EF569186 (Biedrzycka and Radwan 2008; Biedrzycka et al. 2011); Eastern woodchuck (Marmota monax) Mamo‐DRB1A: KJ675569 (Moreno‐Cugnon et al. 2015); European marmot (Marmota marmota) Mama‐DRB: JQ837902 (Kuduk et al. 2012), Abert's squirrel (Sciurus aberti) Scab‐DRB: AAA42356; and human (Homo sapiens) HLA‐DRB: NP_002115.